WebThe TSC1 gene provides instructions for producing a protein called hamartin. Within cells, hamartin interacts with a protein called tuberin, which is produced from the TSC2 gene. These two proteins help control cell growth and division (proliferation) and cell size. Proteins that normally prevent cells from growing and dividing too fast or in ... WebA reduction in mosaic regularity was observed for Lhx2-Cre:Tsc1f/f mice. The data represent the mean±s.e.m. of three mice from each genotype. (F) Quantification of RGC number in the tangential plane of control and Lhx2-Cre:Tsc1f/f mice. A decrease in the number of Brn3+ cells was observed in Lhx2-Cre:Tsc1f/f mice.

Epileptogenesis and treatment options in a tuberous sclerosis …

WebPurchase TSC1F Plumbing Material for Water Supply, ESLON Fitting, "HI-TS / Gold / TS / HI Transparent Blue" Cap from SEKISUI CHEMICAL and many other industrial components. … WebMethods: Atg5 Flox/Flox (Atg5F/F) and Tsc1F/F mice were crossed with albumin-Cre mice to generate liver-specific Atg5 knockout (L-Atg5 KO), L-Tsc1 KO and L-Atg5/Tsc1 double KO … flap the bat

利用肝脏特异性TSC1敲除小鼠建立酒精性肝炎模型 免疫 肝细胞 纤 …

WebBoth TSC1f/f LysM-Cre+ and LysM-Cre- mice were aerogenously infected with M. tuberculosis H37Rv with 200-300 bacilli per lung. Bacterial burdens were measured by … WebOverall design: p62F/F and Tsc1 F/F mice (Mori et al., 2009; Muller et al., 2013) were backcrossed to C57BL/6 mice for at least 7 generations, and then bred with Alb-Cre transgenic mice (also on C57BL/6 background) to generate p62F/F; Alb-Cre (p62Δhep) and Tsc1F/F; Alb-Cre (Tsc1Δhep)mice, respectively. p62Δhep mice were crossed to Tsc1Δhep ... WebmTORC1 is a key regulator of cell metabolism and lymphocyte proliferation. mTORC1 is inhibited by the tuberous sclerosis complex (TSC), a heterodimer of TSC1 and TSC2. Deletion of either genes results in robust activation of mTORC1. Mature B cells flaps out