Web7 sep. 2024 · Megalin is an endocytic receptor abundantly expressed in proximal tubular epithelial cells and other calciotropic extrarenal cells expressing vitamin D metabolizing enzymes, such as bone and parathyroid cells. Web8 mrt. 2024 · INTRODUCTION. Megalin is a large membrane protein of ~600 kDa in size, located on the apical membrane of proximal tubule epithelial cells (PTECs), and is one of the main endocytic receptors in these cells (6, 21).Megalin binds many low-molecular-weight ligands and plays a crucial role in the reabsorption of glomerular-filtered proteins ().
Megalin - Binding Proteins - Click to Cure Cancer
WebMegalin Antagonizes Activation of the Parathyroid Hormone Receptor. × Close Log In. Log in with Facebook Log in with Google. or. Email. Password. Remember me on this computer. or reset password. Enter the email address you signed up with and we'll email you a reset link. Need an account? Click here to sign up. Log In Sign Up. Log In; Sign Up ... Web4 jan. 2024 · Megalin Blockade with Cilastatin Suppresses Drug-Induced ... In addition, kidney injury molecule-1 (KIM-1), an established kidney injury marker, was expressed … rehoboth gallup
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Web7 sep. 2024 · Megalin is an endocytic receptor abundantly expressed in proximal tubular epithelial cells and other calciotropic extrarenal cells expressing vitamin D metabolizing … Web16 mei 2016 · Given that kidney filtration of the blood results in 180 l per day (refs 7, 8) of glomerular ultrafiltrate containing 10–30 g l −1 of low-molecular weight proteins 6, 9, Megalin and Cubilin... WebAMN (Fig. 73.3) has a molecular weight ranging from 38–50 kDa 92 and was initially recognized as being involved in normal development of the middle portion of the primitive … rehoboth gallup nm