Cst smad3
Web200 ul 3102S Smad2/3 Antibody 100 ul 9523S Smad3 (C67H9) Rabbit mAb 100 ul 9132S. Stat3 Antibody. 100 ul 9903S U0126 (MEK1/2 Inhibitor) 5 mg 2479S VEGF Receptor 2 (55B11) Rabbit mAb 100 ul 3932S. Vimentin (R28) Antibody. 100 ul. 二抗广州聚研CST 现货. 目录号 产品说明. 规格. 7076S Anti-mouse IgG, HRP-linked Antibody 1 ml 7074S WebPhospho-Smad2 (Ser465/467)/Smad3 (Ser423/425) (D27F4) Rabbit mAb (PE Conjugate) 11979S 美国Cell Signaling Technology(CST) 100μl TGF-beta/Smad Signaling Monoclonal Antibody 4C Phospho-BACH1/BRIP1 (Thr1133) Antibody 11983S 美国Cell Signaling Technology(CST) 100μl Cell Cycle / Checkpoint Polyclonal Antibody -20C
Cst smad3
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Web960化工网为您提供TGF-β Antibody产品详细说明,厂家联系电话,及其相关产品,找TGF-β Antibody, 请联系美国CST中国,,电话: 021-58356288 上960化工网,全国免费电话4000-025-960 WebJun 20, 2024 · Besides AZIN1, reduction of JNK1 was responsible for the pro-fibrotic effects by activation of ERK and p38 kinase, in parallel with the activation of Smad3 (Tao et al., 2016). Therefore, we further examined the modulatory effects of circNFIB on miR-433 target genes and downstream signaling pathways.
WebGet better batch-to-batch reproducibility with a recombinant antibody. Anti-Smad3 antibody [EP568Y] (ab40854) Research with confidence – consistent and reproducible results with every batch. Long-term and scalable supply – powered by recombinant technology for fast production. Success from the first experiment – confirmed specificity ... Highly specific and rigorously validated in-house, Smad3 Antibody (CST #9513) is ready to ship. ... Smad2 and Smad3 become phosphorylated at their carboxyl termini (Ser465 and 467 on Smad2; Ser423 and 425 on Smad3) by TGF-β Receptor I. Phosphorylated Smad 2/3 can complex with Smad4, translocate to the nucleus and regulate gene expression (9-11
WebJul 5, 2024 · Pin1 depletion restored Smad3 protein levels and tumor-suppressive activity, suggesting that the Pin1-Smad3 interaction has a negative impact on canonical Smad3 action. Collectively, the data show that the Pin1-Smad3 interaction, facilitated by CDK-mediated Smad3 phosphorylation, is associated with oncogenic TGFβ signaling and … WebNov 30, 2024 · By contrast, the Smad3 protein level showed no significant change among the different groups (Fig. 5c). As a result, the promotion of MSC osteogenesis is mainly mediated by activation of the BMP2 ...
WebPhospho-Smad3 (Ser423/425) (C25A9) Rabbit mAb detects endogenous levels of Smad3 when phosphorylated at Ser423/425. This antibody does not cross-react with other family members. ... but reactivity has not been tested or confirmed to work by CST. Use of this product with these species is not covered under our Antibody Performance Guarantee.
WebJul 23, 2016 · Clones Smad2,Smad3 Smad7siRNA least90% inhibition targetgenes were chosen furtheranalysis. experimentalprocedures, second thirdpassages eachclone were used. knockdowncells monitoredduring culture under invertedmicroscope. ... were performed codedslides blindedfashion. Western blot Low-molecular weight marker (Cell Signaling … greater manchester fareshareWebSep 15, 2024 · The cell lysate concentration was adjusted to 1 µg/µl. Then, we added the YAP (CST, Rabbit, Cat. No. 14074S), Smad2 (CST, Rabbit, Cat. No. 5339S), and Smad3 (CST, Rabbit, Cat. No. 9523S) primary antibodies to the cell lysate individually. And an equal amount of isotype control (CST, Cat. No. 2729S) was used as a negative control. greater manchester fbuWebSep 1, 2024 · TGF-β1 causes cardiac fibrosis by stimulating Smad3 and PI3K-Akt-GSK-3β signaling pathways. TGF-β1 phosphorylates and activates the highly-conserved cytoplasmic proteins of the SMADs family, and PI3K-Akt-GSK-3β pathway, thereby regulating the expression of the related genes leading to fibrosis. greater manchester fcWebJan 1, 2024 · Level III. New Work Elements go into effect on January 1, 2024. In addition to the Levels I and II knowledge and skills, Level III Technicians are required to demonstrate a thorough knowledge of survey computations, types of surveys and field operations. The individual in this position is well versed with field note reduction and in depth plan ... flint fields horse park michiganWebJan 25, 2024 · A pan acetylation antibody (9441S, CST) was used. H) KAT6A knockdown (KD) decreases the acetylation (Ac-Lys) of SMAD3 in MDA-MB-231 cells. I) Effect of acetyltransferase activity-deficient mutants G657E and C543G/G657E of KAT6A on SMAD3 acetylation. J) MS analysis of acetylation sites of SMAD3 by KAT6A. ... In addition, in … greater manchester falls reportgreater manchester fiiWebMar 12, 2024 · A bleomycin-induced pulmonary fibrosis animal model used SD rats. Morphological changes were analyzed by hematoxylin-eosin staining. RT-qPCR and western blot were used for the detection of the expression of TGF-β1, collagen I, collagen III, E-cadherin, fibronectin and the ratios of p-Smad2/Smad2, p-Smad3/Smad3. greater manchester family hubs